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Table 4 Odds ratio ( OR ) (95% CI) ( p -value) for SNP interactions in SNP (4, 7) combinations

From: Improved branch and bound algorithm for detecting SNP-SNP interactions in breast cancer

 

Statistics

CXCL12*

Genotypes (X)

   

GG

AG

AA

KITLG *

TT

OR a

1.047

1.163

1.685

Genotypes (Y)

CI

0.709-1.546

0.763-1.773

0.706-4.030

p-value

0.849

0.471

0.214

(Ca./Co.)

(66/97)

(54/73)

(13/12)

CT

OR a

0.460

0.823

0.499

CI

0.265-0.793

0.503-1.341

0.106-2.034

p-value

0.003

0.484

0.379

(Ca./Co.)

(22/65)

(33/59)

(3/9)

CC

OR a

0.811

4.342

N.E

CI

0.288-2.221

1.259-16.394

 

p-value

0.817

0.013

 

(Ca./Co.)

(7/13)

(11/4)

 
  1. NOTE - *:SNPs (4, 7) pair with its corresponding genotypes CXCL12-rs1801157- genotype X and KITLG-rs10506957-genotype Y; a: OR in reference to the other group (1.000); CI: Confidence Interval; Ca.: case; Co.: control; N.E: Not estimable.