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Table 5 KEGG pathways and PANTHER classifications associated with top 80 genes selected by BMI

From: A filter-based feature selection approach for identifying potential biomarkers for lung cancer

KEGG pathway name

p-value

Associated genes

Colorectal cancer

1.3809E-4

FOS, MSH2, APC

Pathways in cancer

0.0019

FOS, MSH2, APC, TCEB2

Metabolic pathways

0.0021

ADH6, SAT1, EXT2, TGDS, BTD, PRPS1, AGPS

Biotin metabolism

0.0032

BTD

MAPK signaling pathway

0.0094

DUSP10, MAP2K4, FOS

Cytokine-cytokine receptor interaction

0.0098

CXCR4, ACVR2A, IL13RA1

Toll-like receptor signaling pathway

0.0117

FOS, MAP2K4

Tight junction

0.0196

PPP2R2 D, INADL

Mismatch repair

0.0361

MSH2

Glycosaminoglycan biosynthesis - heparan sulfate

0.0408

EXT2

Pentose phosphate pathway

0.0423

PRPS1

Endocytosis

0.0428

ARAP1, CXCR4

PANTHER classification

p-value

Associated genes

Oxidative stress response

8.6417E-5

TXN, MAP2K4, DUSP10

O-antigen biosynthesis

0.0064

TGDS

T cell activation

0.0083

FOS, B2M

Interleukin signaling pathway

0.0108

IL13RA1, FOS

Apoptosis signaling pathway

0.0133

ATF3, FOS

FGF signaling pathway

0.0135

MAP2K4, PPP2R2D

Axon guidance mediated by Slit/Robo

0.0253

CXCR4

Hypoxia response via HIF activation

0.0408

TXN

Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade

0.0484

FOS