Figure 3
From: FISH Oracle: a web server for flexible visualization of DNA copy number data in a genomic context
Annotated genes and segment data obtained from different array CGH experiments for esophagus, pancreas, prostate, colon and multiple myeloma tumor tissue shown at the 12p11.23 locus. The segment data are taken from the FISH Oracle data. All segments have a mean intensity value greater than 0.5 and therefore represent amplified regions. There are amplifications in the region from about 24.5 Mbp to 25.6 Mbp. The minimal overlapping region covers the area from 25.1 Mbp to 25.35 Mbp. This region contains the genes LRMP, CASC1, LYRM5 and KRAS. KRAS is a known proto oncogene, which may lead to tumor development if amplified [42]. The minimal region including KRAS is shown in a red box.