Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma

Table 2 Hot spot-, cold spot- and clinicopathological feature-associated microsatellite markers identified in HNSCC tissue compartments

Using laser capture microdissection, epithelium and stromal tissue compartments of squamous cell cancer lesions of head neck from 122 samples were acquired. 366 microsatellite markers were used to identify significantly higher/lower frequency of LOH/AI at a marker or markers compared with other markers along the same chromosome. The table shows the number of cold spot, hot spot or clinicopathological features (CPF) identified in epithelium only, stroma only, and both in epithelium and stroma.