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Table 5 Proteins differently expressed between smoker and no-smoker controls and between PLCH patients and controls.

From: Proteome analysis of bronchoalveolar lavage in pulmonary langerhans cell histiocytosis

No. of spot Protein name AC Theoretical
pI/Mr (KDa)
Experimental
pI/Mr (KDa)
Mascot search result Mean %V ± SD × 10-4 1-way ANOVA pvalue Folds in Localization
      No. of matched peptide Sequence coverage (%) Score nsc sc PLCH   Nsc-sc Nsc-PLCH Sc-PLCH  
PLCH < nsc and/or sc
25 Polymeric immunoglobulin receptor P01833 5.58 5.14 10 18 129 2901±438§ 3037±1038¥ 911±694¥§ 1.31E-03 1.04 3.18§ 3.33¥ Cell membrane
    84429 87377            
26 Thioredoxin P10599 4.82 4.67 6 40 82 665±113 1492±819¥ 230±235¥ 0,005 2.24 2.89 6.48¥ Cytoplasm-Secreted
    12015 12098            
27 Plastin-2 P13796 5.2 5.19 10 21 102 873±355 1272±320¥ 453±386¥ 0,01 1.45 1.92 2.80¥ Cytoplasm-Cytoskeleton-Cell junktion
    70815 61983            
28 Serum albumin P02768 5.92 6.04 8 14 92 1830±647 2980±827¥ 1239±1363¥ 0,04 1.62 1.47 2.40¥ Plasma
    71317 57513            
29 Serum albumin, fragment P02768 5.92 6.09 6 9 74 278±137 405±224¥ 124±83¥ 0,049 1.45 2.24 3.26¥ Plasma
  N-term   71317 31059            
30 ADP-ribosylation factor-like protein 3 P36405 6.74 7.37 6 52 107 305±161 621±331¥ 142±49¥ 0,012 2.03 2.14 4.37¥ Membrane
    20614 21404            
31 Alpha-1B-glycoprotein P04217 5.58 5.16 8 22 109 1370±414§ 1163±443 663±83§ 0,022 1.17 2.06§ 1.75 Plasma
    54809 75685            
  1. This table is divided in two parts: the first part includes protein spots significantly down-regulated in non-smoker compared to smoker controls; the second part includes spots up-regulated in non-smoker than smoker controls.