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Figure 2 | Journal of Clinical Bioinformatics

Figure 2

From: Profiling the human response to physical exercise: a computational strategy for the identification and kinetic analysis of metabolic biomarkers

Figure 2

Inferred network. The resulting kinetic network (Ï„ = 73) exhibits lactate, alanine, C2 and C3 as major hubs (green color) in the center of the network with the highest degree of connectivity. Note that an edge between metabolite m i and m j indicates a pBI value of the absolute logarithmic ratio of m i and m j greater than Ï„ (e.g., for the edge between C2 and C16 |pBI(|log2 (C2/C16)|)| > 73). Identified key metabolites during physical activity could also be validated by literature [22, 23, 32]. The number following the underscore of acyl-carnitines symbols indicates the number of double binds of the carbon-carbon bonds (e.g., for C10_1 the number of double binds is 1). The network is visualized using Cytoscape [33]. images/pbiGraph.png.

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Journal of Clinical Bioinformatics

ISSN: 2043-9113