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Table 1 Marker Concentration Changes

From: The impact of sample storage time on estimates of association in biomarker discovery studies

Date of sample collection Concentration measured % change
  at sample collection Sept 2009  
  CA 15-3   
Nov 1997 166 187 12.65
Oct 1998 29 33 13.79
Apr 1995 10 12 20.00
Feb 2001 21 19 -9.52
Apr 2001 23 24 4.35
Feb 1999 33 34 3.03
Sep 2000 26 33 26.92
Sep 2000 24 33 37.50
Sep 2000 15 17 13.33
Sep 2000 12 16 33.33
Nov 1999 884 986 11.54
  CA125   
Feb 1999 83 96 15.66
Feb 1999 < LOD < LOD  
Feb 1999 < LOD < LOD  
Feb 1999 51 69 35.29
Feb 1999 < LOD < LOD  
Sep 2000 77 73 -5.19
Sep 2000 33 32 -3.03
Sep 1998 106 105 -0.94
Oct 1998 1273 2026 59.15
  1. LOD = limit of detection
  2. Concentrations of two markers, CA 15-3 and CA125, measured at the time of freezing and then again after a long term storage. Measurements with concentrations below the limit of detection were excluded from further analysis.