Table 2 Top 22 single drug targets for prostate cancer
Drug name | Target Name | F(Du) | AG(Du) |
|---|---|---|---|
Casodex, Eulexin, Striant Bucl | AR | 45.88 | 5576.87 |
Erlotinib | EGFR | 29.54 | 4272.24 |
Budesonide | NR3C1 | 12.52 | 4677.47 |
Estramustine | ESR1 | 10.88 | 4597.53 |
5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid | CASP3 | 10.84 | 3914.63 |
Glycerol | TGFBR2 | 10.40 | 2943.79 |
ATL1101 | IGF1R | 10.29 | 4080.81 |
Dodecane-Trimethylamine | PTPN11 | 8.43 | 3678.47 |
Fica | CASP7 | 7.80 | 3276.11 |
Diphenylacetic Acid | CTSB | 6.62 | 3391.85 |
Marimastat | MMP2 | 6.29 | 3518.70 |
| Â | SLC25A6 | 5.75 | 3994.49 |
| Â | AURKA | 5.60 | 3256.80 |
Phenelzine | MAOA | 5.40 | 3067.25 |
| Â | LGALS3BP | 5.34 | 2902.46 |
| Â | LCK | 5.22 | 3607.57 |
| Â | THBS1 | 5.10 | 2451.01 |
Insulin, porcine | INSR | 4.32 | 2344.82 |
Trastuzumab | ERBB2 | 4.31 | 3351.47 |
Staurosporine | CDK2 | 4.00 | 3692.15 |
K-252a | MET | 3.90 | 2318.86 |
| Â | TFRC | 3.83 | 2611.10 |