Figure 3
From: A comparative analysis of protein targets of withdrawn cardiovascular drugs in human and mouse
Binding patterns of troglitazone with its targets. Panel (A) illustrates interactions between troglitazone and human PPAR-gamma, while (B) represents interactions between drug and corresponding mouse target. Panel (C) illustrates interactions between troglitazone and human PAI, while (D) represents interactions between drug and corresponding mouse target. The residue substitutions in the binding pocket are labeled.