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Table 1 Probability and time of 1 st metastasis formation

From: A dynamic model for tumour growth and metastasis formation

  MS-Model GDR-Model
Dissemination from primary Metastases growth characteristis Single Cell size [103 µm3] Metastasis Formation [%] Mean time of 1st colonizing cell [months] Metastasis Formation [%] Mean time of 1st colonizing cell [months]
Prim. Meta. Visible at pT2 Visible at pT4 Before pT1 Visible at pT2 Visible at pT4 Before pT1
V P 1 1 95.0 100.0 100.0 22.6 99.5 100.0 100.0 23.7
2 1 93.3 100.0 100.0 22.1 97.0 100.0 100.0 23.3
V2/3 P 1 1 36.6 100.0 100.0 27.5 48.2 100.0 100.0 28.3
2 1 32.3 100.0 100.0 27.5 40.5 100.0 100.0 28.1
1 0.5 41.2 100.0 100.0 23.9 60.7 100.0 100.0 24.7
A 1 1 10.6 87.9 100.0 16.2 5.5 22.7 71.6 13.4
2 1 9.5 79.6 100.0 17.1 5.8 24.2 89.1 14.1
1 0.5 10.3 90.5 100.0 14.5 6.0 25.2 77.7 11.9
V1/3 P 1 1 6.9 42.4 45.9 53.1 9.4 63.9 61.2 45.2
2 1 6.6 44.4 59.2 51.2 8.4 58.2 76.6 45.2
1 0.5 7.9 54.1 63.9 49.4 10.9 75.4 80.3 40.0
A 1 1 4.0 17.3 98.1 29.5 2.5 6.1 15.2 22.7
2 1 4.5 17.2 99.3 30.7 3.5 7.9 22.1 23.6
1 0.5 5.0 20.2 99.8 25.8 3.5 8.7 19.9 19.6