From: A dynamic model for tumour growth and metastasis formation
 | MS-Model | GDR-Model | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Dissemination from primary | Metastases growth characteristis | Single Cell size [103 µm3] | Metastasis Formation [%] | Mean time of 1st colonizing cell [months] | Metastasis Formation [%] | Mean time of 1st colonizing cell [months] | |||||
Prim. | Meta. | Visible at pT2 | Visible at pT4 | Before pT1 | Visible at pT2 | Visible at pT4 | Before pT1 | ||||
V | P | 1 | 1 | 95.0 | 100.0 | 100.0 | 22.6 | 99.5 | 100.0 | 100.0 | 23.7 |
2 | 1 | 93.3 | 100.0 | 100.0 | 22.1 | 97.0 | 100.0 | 100.0 | 23.3 | ||
V2/3 | P | 1 | 1 | 36.6 | 100.0 | 100.0 | 27.5 | 48.2 | 100.0 | 100.0 | 28.3 |
2 | 1 | 32.3 | 100.0 | 100.0 | 27.5 | 40.5 | 100.0 | 100.0 | 28.1 | ||
1 | 0.5 | 41.2 | 100.0 | 100.0 | 23.9 | 60.7 | 100.0 | 100.0 | 24.7 | ||
A | 1 | 1 | 10.6 | 87.9 | 100.0 | 16.2 | 5.5 | 22.7 | 71.6 | 13.4 | |
2 | 1 | 9.5 | 79.6 | 100.0 | 17.1 | 5.8 | 24.2 | 89.1 | 14.1 | ||
1 | 0.5 | 10.3 | 90.5 | 100.0 | 14.5 | 6.0 | 25.2 | 77.7 | 11.9 | ||
V1/3 | P | 1 | 1 | 6.9 | 42.4 | 45.9 | 53.1 | 9.4 | 63.9 | 61.2 | 45.2 |
2 | 1 | 6.6 | 44.4 | 59.2 | 51.2 | 8.4 | 58.2 | 76.6 | 45.2 | ||
1 | 0.5 | 7.9 | 54.1 | 63.9 | 49.4 | 10.9 | 75.4 | 80.3 | 40.0 | ||
A | 1 | 1 | 4.0 | 17.3 | 98.1 | 29.5 | 2.5 | 6.1 | 15.2 | 22.7 | |
2 | 1 | 4.5 | 17.2 | 99.3 | 30.7 | 3.5 | 7.9 | 22.1 | 23.6 | ||
1 | 0.5 | 5.0 | 20.2 | 99.8 | 25.8 | 3.5 | 8.7 | 19.9 | 19.6 |