| Molecular Function/Pathway | Enrichment Rank by p-value* | Enrichment P-value (BH corrected) | Enrichment level (observed/expected) | Pathway mutational spectrum:% of genes | Pathway Mutational Prevalence: % of tumors | # genes mutated in at least 3 patients |
---|---|---|---|---|---|---|---|
KEGG | ECM-receptor Interaction | 1 | 3.35x10-11 | ~4.5X | 74% (62/84) | 40% (127/316) | 30 |
 | Focal Adhesion | 2 | 2.62x10-9 | ~2.9X | (61%) 122/199 | 58% (183/316) | 45 |
 | Calcium Signaling | 3 | 2.05x10-8 | ~2.9X | 63% (112/179) | 48% (153/316) | 40 |
Gene Ontology | Cell Adhesion | 1 | 1.03x10-25 | ~2.5X | 64% (366/576) | 89% (281/316) | 156 |
 | Developmental process | 14 | 1.03x10-15 | ~1.5X | 49% (430/869) | 90% (284/316) | 375 |
 | Extracellular Matrix | 19 | 2.56x10-14 | ~2.8X | 53% (80/150) | 40% (127/316) | 76 |