Table 2 Differentially expressed probes/genes in the setting of peripheral arterial disease

219326_s_at

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

B3GNT2

0.032

1.53

205681_at

BCL2-related protein A1

BCL2A1

0.008

1.73

215440_s_at

brain expressed, X-linked 4

BEX4

0.004

1.50

1554229_at

chromosome 5 open reading frame 41

C5orf41

0.004

1.51

202284_s_at

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

CDKN1A

0.024

1.62

208791_at

clusterin

CLU

0.029

1.84

208792_s_at

clusterin

CLU

0.038

1.83

226702_at

cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial

CMPK2

0.039

1.54

225557_at

cysteine-serine-rich nuclear protein 1

CSRNP1

0.032

1.57

211919_s_at

chemokine (C-X-C motif) receptor 4

CXCR4

0.039

1.59

208811_s_at

DnaJ (Hsp40) homolog, subfamily B, member 6

DNAJB6

0.004

1.53

204751_x_at

desmocollin 2

DSC2

0.007

1.68

226817_at

desmocollin 2

DSC2

0.007

1.99

201044_x_at

dual specificity phosphatase 1

DUSP1

0.043

1.94

209457_at

dual specificity phosphatase 5

DUSP5

0.008

1.56

219872_at

family with sequence similarity 198, member B

FAM198B

0.003

1.51

207674_at

Fc fragment of IgA, receptor for

FCAR

0.012

1.99

211307_s_at

Fc fragment of IgA, receptor for

FCAR

0.012

1.72

221345_at

free fatty acid receptor 2

FFAR2

0.007

2.34

209189_at

FBJ murine osteosarcoma viral oncogene homolog

FOS

0.01

1.70

213524_s_at

G0/G1switch 2

G0S2

0.024

3.90

207387_s_at

glycerol kinase

GK

0.035

1.61

208524_at

G protein-coupled receptor 15

GPR15

0.024

1.66

211555_s_at

guanylate cyclase 1, soluble, beta 3

GUCY1B3

0.011

1.59

214455_at

histone cluster 1, H2bg

HIST1H2BG

0.041

1.88

1555464_at

interferon induced with helicase C domain 1

IFIH1

0.026

1.55

211506_s_at

interleukin 8

IL8

0.022

3.69

220266_s_at

Kruppel-like factor 4 (gut)

KLF4

0.034

1.61

208960_s_at

Kruppel-like factor 6

KLF6

0.038

1.88

217738_at

nicotinamide phosphoribosyltransferase

NAMPT

0.027

1.73

217739_s_at

nicotinamide phosphoribosyltransferase

NAMPT

0.021

1.80

243296_at

nicotinamide phosphoribosyltransferase

NAMPT

0.008

2.00

203574_at

nuclear factor, interleukin 3 regulated

NFIL3

0.008

1.55

216015_s_at

NLR family, pyrin domain containing 3

NLRP3

0.041

1.52

205660_at

2'-5'-oligoadenylate synthetase-like

OASL

0.035

1.50

224102_at

purinergic receptor P2Y, G-protein coupled, 12

P2RY12

0.022

1.56

201120_s_at

progesterone receptor membrane component 1

PGRMC1

0.008

1.54

210845_s_at

plasminogen activator, urokinase receptor

PLAUR

0.004

1.60

211924_s_at

plasminogen activator, urokinase receptor

PLAUR

0.004

1.76

204285_s_at

phorbol-12-myristate-13-acetate-induced protein 1

PMAIP1

0.005

1.52

202014_at

protein phosphatase 1, regulatory (inhibitor) subunit 15A

PPP1R15A

0.012

1.96

37028_at

protein phosphatase 1, regulatory (inhibitor) subunit 15A

PPP1R15A

0.008

1.87

1554997_a_at

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

PTGS2

0.025

2.77

200730_s_at

protein tyrosine phosphatase type IVA, member 1

PTP4A1

0.03

1.62

1569599_at

SAM domain, SH3 domain and nuclear localization signals 1

SAMSN1

0.006

1.72

222088_s_at

solute carrier family 2 (facilitated glucose transporter), member 14

SLC2A14

0.033

1.56

215223_s_at

superoxide dismutase 2, mitochondrial

SOD2

0.038

1.57

205214_at

serine/threonine kinase 17b

STK17B

0.004

1.60

210190_at

syntaxin 11

STX11

0.003

1.65

1552542_s_at

T-cell activation RhoGTPase activating protein

TAGAP

0.004

1.66

235086_at

thrombospondin 1

THBS1

0.038

2.12

221060_s_at

toll-like receptor 4

TLR4

0.025

1.82

206116_s_at

tropomyosin 1 (alpha)

TPM1

0.013

1.58

241133_at

T cell receptor beta constant 1

TRBC1

0.048

1.91

Downregulated Probe ID

Gene name (HUGO)

Gene name

P-value

FCA

239661_at

AF4/FMR2 family, member 1

AFF1

0.022

1.63

220467_at

--

AL590452.1

0.043

1.56

236921_at

--

AL592494.5

0.027

1.64

238807_at

ankyrin repeat domain 46

ANKRD46

0.038

1.53

216198_at

activating transcription factor 7 interacting protein

ATF7IP

0.026

1.50

236307_at

BTB and CNC homology 1, basic leucine zipper transcription factor 2

BACH2

0.039

2.11

236796_at

BTB and CNC homology 1, basic leucine zipper transcription factor 2

BACH2

0.015

1.70

244172_at

B-cell linker

BLNK

0.043

1.78

227576_at

BMP2 inducible kinase-like

BMP2KL

0.048

1.83

244425_at

chromosome 14 open reading frame 43

C14orf43

0.03

1.65

238635_at

chromosome 5 open reading frame 28

C5orf28

0.00E+00

2.03

232330_at

chromosome 7 open reading frame 44

C7orf44

0.046

1.58

239545_at

CAS1 domain containing 1

CASD1

0.024

1.64

1564164_at

DENN/MADD domain containing 1B

DENND1B

0.048

1.53

230653_at

DIS3 mitotic control homolog (S. cerevisiae)-like 2

DIS3L2

0.039

1.77

244876_at

early B-cell factor 1

EBF1

0.034

1.50

230983_at

family with sequence similarity 129, member C

FAM129C

0.043

1.63

1563674_at

Fc receptor-like 2

FCRL2

0.041

1.68

228623_at

FTX transcript, XIST regulator (non-protein coding)

FTX

0.048

1.82

1562289_at

G protein-coupled receptor 141

GPR141

0.036

1.66

206785_s_at

killer cell lectin-like receptor subfamily C, member 1

KLRC1

0.035

1.69

224559_at

metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)

MALAT1

0.032

1.68

243736_at

methyltransferase like 15

METT5D1

0.034

1.59

232478_at

MIR181A2 host gene (non-protein coding)

MIR181A2HG

0.021

1.52

228623_at

FTX transcript, XIST regulator (non-protein coding)

FTX

0.048

1.82

243310_at

--

--

0.017

1.52

239673_at

nuclear receptor subfamily 3, group C, member 2

NR3C2

0.037

1.94

240128_at

5'-nucleotidase, cytosolic III

NT5C3

0.03

1.57

1559054_a_at

protein phosphatase 1, regulatory (inhibitor) subunit 7

PPP1R7

0.004

1.60

238875_at

RANBP2-like and GRIP domain containing 1

RGPD1

0.026

1.50

241838_at

--

RP1-167A14.2

0.034

1.54

242239_at

--

RP11-139J15.3

0.008

1.55

228390_at

--

RP11-659G9.3001

0.033

1.57

213939_s_at

RUN and FYVE domain containing 3

RUFY3

0.035

1.50

244267_at

SATB homeobox 1

SATB1

0.025

1.81

236561_at

transforming growth factor, beta receptor 1

TGFBR1

0.033

1.66

236427_at

WW domain containing oxidoreductase

WWOX

0.035

1.61

1556543_at

zinc finger, CCHC domain containing 7

ZCCHC7

0.041

1.68

228157_at

zinc finger protein 207

ZNF207

0.027

2.01

236562_at

zinc finger protein 439

ZNF439

0.015

1.51

240155_x_at

zinc finger protein 479

ZNF479

0.012

1.52

1558486_at

zinc finger protein 493

ZNF493

0.012

1.53