|
Data
|
Peptides
|
Proteins
|
Mean TO
|
RandomTO
|
p-value
|
|---|
|
Sarcopenia
|
2845
|
685
|
0.089
|
0.004
|
2.09e-14
|
|
SARS
|
2008
|
707
|
0.025
|
0.004
|
2.2e-16
|
|
Influenza
|
989
|
493
|
0.028
|
0.005
|
8.99e-16
|
- Results from a two-sample t-test between topological overlap (TO) of peptides derived from the same protein versus peptides selected at random. This result statistically shows that the connectivity for a protein’s constituent peptides is far from random. Network topology may be useful for resolving cases of degenerate peptide mapping, increasing confidence in protein identification.
