Table 3 miRNAs validated targets, hierarchical order

DICER1

5

LIN28

2

CD46

1

G6PD

1

MAP2K3

1

POU2F2

1

SPI1

1

CDKN1A

4

MAPK8

2

CD47

1

GABPA

1

MAP3K12

1

POU4F2

1

SRGAP2

1

NFKB1

4

MECP2

2

CDC14A

1

GHRHR

1

MAP3K9

1

PPARG

1

ST3GAL4

1

TP53

4

MITF

2

CDC20B

1

GRB2

1

MAPK14

1

PPIG

1

STAT3

1

VEGFA

4

MYCN

2

CDC25C

1

GRIA1

1

MAPK3

1

PPP1R13L

1

STK39

1

APC

3

PAK3

2

CDC42

1

GRIN2A

1

MAPKAPK2

1

PRB1

1

STMN2

1

BCL2

3

PROM1

2

CDH1

1

GRIN2B

1

MCL1

1

PRDM1

1

SYNE1

1

CD44

3

PTEN

2

CDK4

1

GRM3

1

MDC1

1

PRKAR1A

1

TARBP2

1

CDC25A

3

SCPEP1

2

CDKN1B

1

GRM7

1

MDM2

1

PRMT5

1

TBK1

1

CDK6

3

SIRT1

2

CEBPB

1

GSX2

1

MDM4

1

PRNP

1

TCF21

1

EIF2C1

3

SOAT1

2

CHEK1

1

GULP1

1

MEIS2

1

PTPN12

1

TCF3

1

EIF2C2

3

SSSCA1

2

CHRD

1

HBEGF

1

MEST

1

PTPN13

1

TCL1A

1

HDAC9

3

STMN1

2

CISH

1

HDAC1

1

MET

1

PXMP2

1

TGFBR2

1

IL1B

3

TACSTD1

2

CKAP4

1

HDAC2

1

MGST1

1

RAB22A

1

TGIF2

1

KRAS

3

TLR4

2

CNN3

1

HELLS

1

MMP13

1

RAB34

1

TIMM8A

1

MYC

3

TP73

2

COL11A2

1

HES1

1

MOCOS

1

RAG2

1

TLR2

1

RNASEN

3

WNT1

2

COL2A1

1

HGF

1

MPI

1

RASSF1

1

TNRC6A

1

AKT1

2

ZEB1

2

COL9A1

1

HLCS

1

MYB

1

RB1

1

TOM1

1

ATN1

2

ACSL1

1

COMP

1

HMG2L1

1

MYBL1

1

RBBP6

1

TOP2B

1

BACE1

2

ACTB

1

CREBZF

1

HMOX1

1

MYD88

1

RCOR1

1

TRIM63

1

BCL6

2

AMELX

1

CRIM1

1

HNF4A

1

MYOD1

1

RELB

1

TRPM3

1

BDNF

2

ANLN

1

CSF1

1

HOXA5

1

NBN

1

REST

1

TWIST1

1

BIRC3

2

ANP32B

1

CTNNB1

1

HRB

1

NDRG1

1

RGS3

1

UBL4A

1

CCND1

2

ARCN1

1

CTNNBIP1

1

HUWE1

1

NDUFA2

1

RNMT

1

VAMP2

1

CCNE2

2

ARIH2

1

CXCL12

1

IGF1

1

NEUROD1

1

RNPC3

1

VDR

1

CDKN2A

2

ATF6

1

CYP2A6

1

IGFALS

1

NEUROG3

1

ROBO2

1

WEE1

1

CDKN2D

2

ATP2A2

1

CYP3A4

1

IKBKB

1

NF2

1

ROS1

1

WISP2

1

CEBPA

2

ATP6V1B2

1

DCT

1

IL2RA

1

NFE2L2

1

RPE

1

XPO5

1

COX8A

2

AXIN2

1

DDIT3

1

IL7R

1

NFYC

1

RPS19

1

YY1

1

CREB1

2

BAMBI

1

DDIT4

1

ING2

1

NOG

1

RTEL1

1

ZAP70

1

DDX20

2

BAX

1

DDX4

1

IRAK1

1

NOL3

1

RUNX1

1

ZEB2

1

DGCR8

2

BBC3

1

DKK2

1

IRAK2

1

NOS2A

1

RUNX2

1

ZNF135

1

E2F1

2

BCR

1

DLL1

1

IRF1

1

NOS3

1

RUNX3

1

ZNF77

1

E2F3

2

BNIP3L

1

DNMT1

1

IRF9

1

NOTCH1

1

SEC24D

1

ZNF828

1

E2F5

2

BRAP

1

ECD

1

IRS1

1

NPAT

1

SEMA6A

1

ZNRD1

1

ELSPBP1

2

BRCA1

1

EDG6

1

JAG1

1

NPC1

1

SERPINE1

1

EPHB2

2

C1orf183

1

EGFL7

1

JARID1B

1

NR1H4

1

SFRP1

1

ERBB2

2

C1orf61

1

EGFR

1

KCNMA1

1

NR2E1

1

SFRS2

1

EZH2

2

C9orf127

1

EIF2C4

1

KIF23

1

NRAS

1

SH2B2

1

FASN

2

CALB1

1

ELAVL1

1

KIT

1

NTRK3

1

SLC11A1

1

FOXO1

2

CAV1

1

ELAVL2

1

LAMC2

1

OCA2

1

SLC12A1

1

FOXP1

2

CBX7

1

ELK3

1

LARP4

1

PAK1

1

SLC22A3

1

FRAP1

2

CCND2

1

ENAM

1

LARP6

1

PAWR

1

SLC27A4

1

GEMIN4

2

CCND3

1

ERBB4

1

LEF1

1

PAX6

1

SLC2A1

1

HMGA2

2

CCNE1

1

ETS1

1

LIF

1

PDGFA

1

SLC7A5

1

IFNG

2

CCNF

1

FGF8

1

LMX1A

1

PEA15

1

SMARCA5

1

IL6

2

CCPG1

1

FMR1

1

LOX

1

PHGDH

1

SND1

1

JAK2

2

CD19

1

FOXG1

1

LRPAP1

1

PIK3CA

1

SOCS1

1

JUN

2

CD28

1

FOXJ1

1

MAP1LC3A

1

PIWIL1

1

SOX2

1

KLF4

2

CD4

1

FZR1

1

MAP2K1

1

PMP22

1

SOX9

1