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Table 4 Putative LMNA ceRNAs GO functions

From: A ceRNA analysis on LMNA gene focusing on the Hutchinson-Gilford progeria syndrome

GO Annotation

False Discovery Rate

post-transcriptional gene silencing by RNA

8.71E-4

gene silencing by miRNA

8.71E-4

post-transcriptional gene silencing

8.71E-4

cellular response to abiotic stimulus

1.11E-3

response to abiotic stimulus

1.11E-3

gene silencing by RNA

1.11E-3

production of miRNAs involved in gene silencing by miRNA

2.64E-3

cell ageing

2.64E-3

cyclin-dependent protein kinase holoenzyme complex

2.64E-3

dsRNA fragmentation

2.8E-3

production of small RNA involved in gene silencing by RNA

2.8E-3

gene silencing

3.84E-3

regulation of homeostatic process

3.84E-3

ageing

3.84E-3

regulation of cyclin-dependent protein kinase activity

3.84E-3

regulation of cell motility

4.01E-3

cellular response to dsRNA

4.29E-3

regulation of protein serine/threonine kinase activity

4.61E-3

regulation of cellular component movement

4.61E-3

regulation of locomotion

4.61E-3

response to dsRNA

4.94E-3

positive regulation of protein phosphorylation

7.51E-3

response to radiation

8.64E-3

cellular response to hypoxia

8.97E-3

cellular senescence

9.78E-3

positive regulation of phosphorylation

9.95E-3

positive regulation of phosphorus metabolic process

1.02E-2

response to drug

1.02E-2

positive regulation of phosphate metabolic process

1.02E-2

cellular response to oxygen levels

1.02E-2

RNA helicase activity

1.12E-2

vascular endothelial growth factor receptor signaling pathway

1.74E-2

Ras guanyl-nucleotide exchange factor activity

1.74E-2

positive regulation of endothelial cell migration

1.8E-2

regulation of gene expression, epigenetic

1.8E-2

cellular response to radiation

2.08E-2

regulation of cell migration

2.15E-2

cellular response to vascular endothelial growth factor stimulus

2.15E-2

nuclear periphery

3.77E-2

positive regulation of angiogenesis

4.47E-2

cellular response to external stimulus

4.49E-2

small GTPase mediated signal transduction

4.49E-2

positive regulation of cell migration

4.49E-2

regulation of endothelial cell migration

4.59E-2

positive regulation of cell motility

4.6E-2

positive regulation of cell adhesion

4.94E-2

positive regulation of locomotion

5.07E-2

positive regulation of cellular component movement

5.1E-2

cellular response to drug

5.53E-2

endoribonuclease activity, producing 5'-phosphomonoesters

5.53E-2

positive regulation of vascular endothelial growth factor receptor signaling pathway

5.53E-2

cyclin-dependent protein kinase activity

5.53E-2

positive regulation of protein modification process

6.09E-2

helicase activity

7.11E-2

G1/S transition of mitotic cell cycle

7.19E-2

regulation of chromosome organization

7.19E-2

regulation of cell aging

7.38E-2

positive regulation of peptidyl-tyrosine phosphorylation

8.34E-2

regulation of vascular endothelial growth factor receptor signaling pathway

8.42E-2

ncRNA metabolic process

9.24E-2

endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'- phosphomonoesters

9.24E-2

regulation of cellular response to growth factor stimulus

9.24E-2

angiogenesis

9.24E-2

endothelial cell migration

9.59E-2

response to hypoxia

9.59E-2

response to oxygen levels

9.92E-2

cellular response to UV

9.92E-2

Cell migration involved in sprouting angiogenesis

9.92E-2