Figure 4
From: A systematic analysis of a mi-RNA inter-pathway regulatory motif
Antigen processing and presentation (APP) pathway (#hsa04612). Antigen processing and presentation (APP) pathway (#hsa04612) including the identified PPLs. The pathway host-gene (NFY-C) expresses a protective intragenic miRNA (miR-30e6) which (2) acts against the expression of the STAT1 transcription factor. (3) STAT1 is responsible for RUNX and UGT8 transcription, that (4) leads to the expression of miR-802 and miR-577 which, if expressed, (5) would target IFN-?, CANX, CALR, CTSB, RFX, HLA-DM, NFY-C.