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Figure 3 | Journal of Clinical Bioinformatics

Figure 3

From: In silicoanalysis of the molecular machinery underlying aqueous humor production: potential implications for glaucoma

Figure 3

Immunohistochemistry of caveolin 1 and clathrin in the ciliary body. Immunofluorescence staining for caveolin 1 (CAV1) and clathrin (CLTR) in human ciliary body sections. Our gene expression data show that CAV1 is significantly different expressed between NPE and PE (p-value < 0.01), with higher expression in NPE and all CLTR coding genes (CLTA, CLTB and CLTC) are highly (>90th P) expressed in both NPE and PE. In this immunofluorescence picture, CAV1 is clearly present in the non-pigmented epithelium (NPE) and possibly also in the pigmented epithelium (PE). We found CLTR in both NPE and PE, especially in the apical plasma membrane. Both CAV1 and CLTR were found in the vascular endothelium of the stroma. Negative controls were for both proteins negative (not shown). Legend: blue = dapi = cell nucleus; red = cy3 = protein of interest.

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Journal of Clinical Bioinformatics

ISSN: 2043-9113