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Table 7 Baseline characteristics of breast cancer cases and controls

From: Improved branch and bound algorithm for detecting SNP-SNP interactions in breast cancer

SNP (Genes)

Chr.

SNP Genotype

Control no. /Case no.

Scoring function

p-value

CC

SN

SP

Average

Odds Ratio

1. rs12812942

12

1-AA

174/128

      

(CD4)

 

2-AT

141/76

0.482

0.372

0.552

0.469

0.733 (0.503-1.068)

0.10

  

3-TT

19/16

0.564

0.111

0.902

0.526

1.145 (0.536-2.438)

0.72

2. rs3136685

17

1-GG

107/77

      

(CCR7)

 

2-AG

180/114

0.462

0.587

0.373

0.474

0.880 (0.594-1.304)

0.57

  

3-AA

47/29

0.523

0.274

0.695

0.357

0.857 (0.478-1.536)

0.68

3. rs2228014

2

1-CC

254/151

      

(CXCR4)

 

2-CT

73/63

0.586

0.294

0.777

0.552

1.452 (0.962-2.191)

0.07

  

3-TT

7/6

0.622

0.382

0.973

0.659

1.442 (0.421-4.880)

0.57

4. rs1801157

10

1-GG

175/106

      

(CXCL12)

 

2-AG

136/98

0.530

0.480

0.562

0.524

1.189 (0.822-1.723)

0.37

  

3-AA

23/16

0.597

0.131

0.884

0.537

1.149 (0.550-2.387)

0.73

5. rs3025039

6

1-CC

211/155

      

(VEGF)

 

2-CT

117/59

0.498

0.276

0.643

0.472

0.687 (0.463-1.016)

0.05

  

3-TT

6/6

0.574

0.037

0.972

0.528

1.361 (0.381-4.870)

0.77

6. rs2287074

16

1-GG

164/113

      

(MMP2)

 

2-AG

139/93

0.505

0.451

0.541

0.499

0.971 (0.670-1.408)

0.93

  

3-AA

31/14

0.553

0.110

0.841

0.510

0.655 (0.316-1.347)

0.25

7. rs10506957

12

1-TT

182/133

      

(KITLG)

 

2-CT

133/69

0.486

0.342

0.578

0.469

0.709 (0.484-1.042)

0.08

  

3-CC

19/18

0.568

0.119

0.905

0.531

1.296 (0.622-2.700)

0.08

  1. NOTE - Chr: Chromosome; Control no: number of control; Case no: number of case; CC: Correct; SN: Sensitivity; SP: Specificity.