Skip to main content

Table 1 Enriched pathways in disjoint catalog analysis

From: Characteristics of cross-hybridization and cross-alignment of expression in pseudo-xenograft samples by RNA-Seq and microarrays

  Human Mouse
  Cross-alignment Cross hybridization Cross-alignment Cross hybridization
1 Cytoskeleton remodeling: keratin filaments Protein folding and maturation: POMC processing Cytoskeleton remodeling: neurofilaments Neurophysiological process: Dopramine D2 receptor transactivation of PDGFR in CNS
2 Signal transduction: cAMP signaling Normal and pathological: TGF-beta mediated regulation of cell proliferation DNA damage: ATM/ATR regulation of G2M checkpoint Transcription role of heterochromatin protein 1 (HP1) family in transcriptional silencing
3 Development: regulation of epithelial to mesenchymal transition (EMT) Cytoskeleton remodeling: TGF, WNT and cytoskeletal remodeling Cell cycle: role of Nek in cell cycle regulation Development: hedgehog and PTH signaling pathways in bone and cartilage development
4 Cell adhesion: gap junctions Signal transduction, Erk interaction: inhibition of Erk Cell cycle: spindle assembly and chromosome separation Cytoskeleton remodeling: neurofilaments
5 Development: transcription regulation of granulocyte development Development: melanocyte development ang pigmentation Development: hedgehog signaling Development: Gastrin in differentiation of the gastric mucosa
6 Cytoskeleton remodelling: regulation of actin cytoskeleton by Rho GTPases Translation: non-genomic (rapid) action of androgen receptor Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF) Blood coagulation: Blood coagulation
7 Cell adhesion: Histamine H1 receptor signlaing in the interruption to cell barrier integrity G-protein signaling : Rap1A regulation pathway Development: FGFR signaling pathway Development thrombopotein-regulated cell processes
8 Development: beta-adrenergic receptors signaling via cAMP Development: GDNF family signaling Muscle contraction: regulation of eNOS activity in endothelial cells Neurophysiologiacal process: ACM regulation of nerve impulse
9 Cytoskeleton remodeling: reverse signaling by Ephrin B DNA damage: role of SUMO in p53 regulation GFTR folding and maturation (normal and CF) Development: WNT5 signaling
10 Regulation of lipid metabolism: regualtion of lipid metabolism by niacin and isoprenaline Muscle contaction: relaxin signaling pathway DNA damage: role of SUMO in p53 regulation Transport: Alpha-2 energenic receptor regulation of Ion channels
  1. Enriched GeneGo pathway maps for human and mouse. Gene lists for pathway analsysis were obtained from the disjoint gene catalog analysis for both cross-hybridization (microarrays) and cross-alignment (RNA-Seq).