Table 4 Demographic and echocardiographic data for African American subjects from population-based cohorts in published GWAS for echocardiographic traits

Age (mean ± SD)

57.9 ± 17.6

58.6 ± 15.9

P = 0.27

59 ± 6

59 ± 6

P = 1

30 ± 4

29 ± 4

P = 3.4x10^-6

55 ± 13

54 ± 13

P = 0.04

Echocardiographic traits

N

1,694

1,140

P-value

698

415

P-value

854

589

P-value

1,884

1,115

P-value

LV diastolic dimension, mm

44.4 ± 7.6

48.5 ± 8.8

<2.2×10^-16

46 ± 6

49 ± 6

<2.2×10^-15

48 ± 4.5

51 ± 4.7

<2.2×10^-16

49 ± 4.1

51 ± 4

<2.2×10^-16

Left atrial dimension, mm

37.4 ± 7.3

40.1 ± 8.0

<2.2×10^-16

39 ± 6

39 ± 6

1

35 ± 5

36 ± 4.8

1.4×10^-4

Not Reported

Not Reported

NA

Aortic root diameter, mm

28.4 ± 3.6

32.8 ± 4.1

<2.2×10^-16

30 ± 4

34 ± 4

<2.2×10^-16

26 ± 3

30 ± 3.5

<2.2×10^-16

30 ± 2.8

34 ± 3

<2.2×10^-16

Posterior wall thickness, mm

10.5 ± 2.2

11.4 ± 2.5

<2.2×10^-16

11 ± 2

12 ± 2

<2.4×10^-15

8 ± 1

9 ± 1.4

<2.2×10^-16

8 ± 1

9 ± 1

<2.2×10^-16

LV systolic dimension, mm

29.0 ± 8.4

33.3 ± 10.7

<2.2×10^-16

Not Reported

Not Reported

NA

Not Reported

Not Reported

NA

29 ± 4

32 ± 5

<2.2×10^-16

Interventricular septal wall thickness, mm

11.0 ± 2.5

12.0 ± 2.8

<2.2×10^-16

12 ± 2

12 ± 3

1

9 ± 2

10 ± 1.6

<2.2×10^-16

9 ± 1

9 ± 1.5

1