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Table 2 Number of markers identified for each disease-biofluid combination

From: Semi-automated literature mining to identify putative biomarkers of disease from multiple biofluids

Breast Cancer Total number of markers found Known markers found (211 possible) Markers producing a significant z-score (>1.0) Known markers with a significant z-score New markers with a significant z-score % new discoveries
Bile 200 26 58 7 51 87.93
Blood 2084 150 196 9 187 95.41
Breastmilk       
CSF 116 8 18 0 18 100.00
Mucus 63 13 8 3 5 62.50
Plasma 1002 88 100 5 95 95.00
Saliva 73 9 10 2 8 80.00
Semen 35 3 6 0 6 100
Serum 1327 106 145 6 139 95.86
SF 21 0 4 0 4 100.00
Stool 68 8 7 3 4 57.14
Sweat 123 15 28 3 25 89.29
Tears 26 2 3 0 3 100.00
Urine 310 32 38 3 35 92.11
Lung Cancer Total number of markers found Known markers found (211 possible) Markers producing a significant z-score (>1.0) Known markers with a significant z-score New markers with a significant z-score % new discoveries
Bile 167 17 25 1 24 96.00
Blood 1863 141 152 7 145 95.39
Breastmilk 77 15 11 2 9 81.82
CSF 106 7 11 1 10 90.91
Mucus 276 27 73 10 63 86.30
Plasma 843 75 65 4 61 93.85
Saliva 53 3 7 1 6 85.71
Semen 11 2 0 0 0 0
Serum 1109 100 103 3 100 97.09
SF 13 2 3 0 3 100.00
Stool 45 2 5 0 5 100.00
Sweat 44 5 4 0 4 100.00
Tears 12 0 1 0 1 100.00
Urine 256 30 56 6 50 89.29
  1. Known markers were determined by identification of the given gene symbol in our known biomarker lists (Additional file 6: Table S1 or Additional file 7: Table S2). Significant markers had a z-score >1.0.