Figure 2
From: FISH Oracle 2: a web server for integrative visualization of genomic data in cancer research
Genomic aberrations in EO-PCA at the 21q22 (ERG) locus. This region focuses on the fusion gene TMPRSS2:ERG[28]. In addition to the chromosome band (1) and gene annotations (2), five data tracks (dataset "Weischenfeldt" in the demo application) are displayed. Track (3) shows all SNVs including six in ERG and two in TMPRSS2. Track (4) displays inter chromosomal translocations, nine of which include ERG and three of which affect TMPRSS2. Track (5) shows several cases of interstitial deletions leading to the TMPRSS2:ERG fusion. The chromosomal ranges of TMPRSS2 and ERG overlapping with deletions are indicated by thin dotted red boxes. Track (6) shows one duplication and track (7) shows seven inversions. Tracks (5), (6) and (7) visualize generic entities, i.e. data specified by genomic coordinates only.