Figure 5

Genomic aberrations in colon and rectal tumors at the 22q12 locus. This region focuses on the frequently translocated gene TTC28. In addition to the chromosome band (1) and gene annotations (2), four data tracks (datasets "TCGA_COAD" and "TCGA_READ" in the demo application) are shown. Track (3) and (4) show CNV intensities in form of deletions (3) and amplifications (4) at a threshold of -0.5 and 0.5 respectively. Track (5) shows SNVs and track (6) shows translocations. The gene TTC28 is affected by six translocations all of which result in a gene fusion.