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Figure 3 | Journal of Clinical Bioinformatics

Figure 3

From: Copy number variation analysis based on AluScan sequences

Figure 3

Poisson binomial distribution of CNVs among samples. The frequency for any window is the percentage of total samples that display a CNV at that window, and the density is the fraction of all the windows analyzed that display a given frequency. Accordingly, CNVs that give rise to frequencies to the right of the cut-off frequency (indicated by red line) represent CNVs that occur at an exceptionally high percentage of samples with p <0.01, and are therefore regarded as recurrent CNVs. The curve shown was calculated using localized CNVs called from the AluScans of the 38 cancer samples in column 2 of Additional file 1: Table S1, in each case employing for comparison the 23-sample reference template.

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