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Volume 5 Supplement 1

Abstracts from the 1st Clinical Research Informatics (CRI) Solutions Day 2014

  • Meeting abstract
  • Open Access

p-BioSPRE - p-medicine Biospecimen Search and Project Request Engine

Journal of Clinical Bioinformatics20155 (Suppl 1) :S20

https://doi.org/10.1186/2043-9113-5-S1-S20

  • Published:

Keywords

  • Integration System
  • Relational Database
  • Data Integration
  • Personalized Medicine
  • Operative Version

Characterisation

Web-based tool, networking of biobanks for personalized medicine, metabiobank, provision of trans-institutional and trans-national access to biobanks.

Description

p-BioSPRE is a metabiobank providing trans-institutional and transnational access to biobanks (Figure 1) while safeguarding patients’ privacy and full biobank autonomy [1].
Figure 1
Figure 1

p-BioSPRE user interface displaying as example patients’ age selection

The p-BioSPRE architecture is based on modular CRIP tools and concepts (a metadata-driven, scalable, and robust system of relational databases with an xml-based query interface) [2]. It mirrors the hub-and-spokes structure proposed by BBMRI for national and international biobank networks. Contrary to biobank registries and catalogs, p-BioSPRE allows for up-to-date queries on a case-by-case and specimen-by-specimen basis. It caters to both: researchers looking for well-annotated human specimens from all disease areas and biobank operators conveniently offering donated specimens and data for research.

p-BioSPRE is in line with the BBMRI requirements for data integration systems and the p-medicine security framework. Its central infrastructure is maintained by Fraunhofer.

Status of development

Access to the operative version of p-BioSPRE is restricted to p-medicine partners. The test and demo version 0.6 is on-line (links below) since May 23, 2014. Evaluation of p-BioSPRE by p-medicine clinical partners is ongoing until 2015.

Users

Researchers looking for stratified human specimens.

Biobank operators looking for projects and partners to make use of donated specimens and data.

Links

Declarations

Acknowledgement

Supported by p-medicine (European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement No 270089).

Authors’ Affiliations

(1)
Fraunhofer IZI-BB, 14476 Potsdam, Germany

References

  1. Schröder C, Heidtke KR, Zacherl N, Zatloukal K, Taupitz J: Safeguarding donors' personal rights and biobank autonomy in biobank networks: the CRIP privacy regime. Cell Tissue Bank. 2011, 12 (1): 233-240.View ArticlePubMedGoogle Scholar
  2. Weiler G, et al: p-BioSPRE – an information and communication technology framework for transnational biomaterial sharing and access. ecancer. 2014, 8: 401-419.Google Scholar

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